All links on this page provide information on vaccines and autoimmunity:
- New Study Shows A Link Between The Hep B Vaccine And Multiple Sclerosis, Again The link between the Hepatitis B vaccine and an increased risk of multiple sclerosis has been something of concern for a number of years since a increase in vaccinations in France led to a dramatic rise in cases of multiple sclerosis, also called MS. Now a new study being reported by Overcoming Multiple Sclerosis shows the link between the vaccine and the rise in MS cases — and explains what the mechanism may be behind this link, as well as other possible vaccine injuries and further supports older studies that found the same link from back in 2004 by a Harvard team.Source: Inquisitir
- Evolution of multiple sclerosis in France since the beginning of hepatitis B vaccination
Since the implementation of the mass vaccination campaign against hepatitis B in France, the appearance of multiple sclerosis, sometimes occurring in the aftermath of vaccinations, led to the publication of epidemiological international studies. This was also justified by the sharp increase in the annual incidence of multiple sclerosis reported to the French health insurance in the mid-1990s. Almost 20 years later, a retrospective reflection can be sketched from these official data and also from the national pharmacovigilance agency.
Source: Réseau Vaccin Hépatite B, 32 rue du Clos Herbert, 14000, Caen, France - Recombinant hepatitis B vaccine and the risk of multiple sclerosis
A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations.
Source: Neurology, the official journal of the American Academy of Neurology - Acquired autoimmunity after viral vaccination is caused by molecular mimicry and antigen complementarity in the presence of an immunologic adjuvant and specific HLA patterns
Acquired autoimmunity syndromes occur after viral vaccinations. Molecular mimicry is involved in these phenomena as is the necessity for the presence of two chemically complimentary antigens and an immunologic adjuvant. The HLA pattern of the host is also an important factor. The example used to explain these phenomena is demyelinating disease that follows hepatitis B vaccination.
Source: Waisbren Clinic, 2315 N. Lake Drive, Suite 815, Milwaukee, WI - Repeated Hep B vaccines do not improve immune defenses
The aim of the study was to (i) evaluate the distribution of lymphocyte subpopulations and the percentage of HBsAg-specific memory B cells in responders and non-responders (ii) assess whether non-responders can be induced to produce antibodies after administration of a booster dose of vaccine (iii) determine whether booster vaccination increases the number of specific memory B cells in non-responders.
Source: Science Direct Vaccine, Vol. 32, Issue 51, Dec. 2014 - Hepatitis B vaccine and liver problems in U.S. children less than 6 years old, 1993 and 1994
Data to assess the benefits and risks of hepatitis B vaccine for the general population of U.S. children are sparse. This study addressed the problem of external validity found in previous studies of high risk populations by evaluating the benefit of hepatitis B vaccination for the general population of American children.
Source: Department of Epidemiology, University of Michigan, Ann Arbor - Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood
The risk of CNS inflammatory demyelination associated with hepatitis B (HB) vaccine is debated, with studies reporting conflicting findings.
Source: Service de Neurologie Pédiatrique, CHU Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre Cedex, France - Autoimmune hazards of hepatitis B vaccine
According to Hippocratic tradition, the safety level of a preventive medicine must be very high, as it is aimed at protecting people against diseases that they may not contract. This paper points out that information on the safety of hepatitis B vaccine (HBV) is biased as compared to classical requirements of evidence-based medicine (EBM).
Source: bd de la République 78000-Versailles, France - Polio programme: Let us declare victory and move on
It was hoped that following polio eradication, immunisation could be stopped. However the synthesis of polio virus in 2002, made eradication impossible. It is argued that getting poor countries to expend their scarce resources on an impossible dream over the last 10 years was unethical.
Source: Department of Paediatrics, St Stephens Hospital, Delhi 110054, India - Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
Autoimmunity to the central nervous system (CNS), especially to myelin basic protein (MBP), may play a causal role in autism, a neurodevelopmental disorder. Because many autistic children harbor elevated levels of measles antibodies, we conducted a serological study of measles-mumps-rubella (MMR) and MBP autoantibodies.
Source: Department of Biology and Biotechnology Center, Utah State University, Logan, Utah - Rheumatic disorders developed after hepatitis B vaccination
A questionnaire was sent to rheumatology departments in nine French hospitals. Criteria for entry were rheumatic complaints of 1 week's duration or more, occurrence during the 2 months following hepatitis B vaccination, no previously diagnosed rheumatic disease and no other explanation for the complaints.
Source: Oxford Journals - Rheumatology, Vol. 38, Issue 10 - Transverse myelitis and vaccines: A multi-analysis
Transverse myelitis is a rare clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord. The pathogenesis of transverse myelitis is mostly of an autoimmune nature, triggered by various environmental factors, including vaccination. Our aim here was to search for and analyze reported cases of transverse myelitis following vaccination.
Source: Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel - Severe Autoimmune Adverse Events Post Herpes Zoster Vaccine: A Case-Control Study of Adverse Events in a National Database
Zoster vaccine is recommended to reduce the incidence of herpes zoster and its complication of postherpetic neuralgia in older adults. However, there have been reports of autoimmune side effects post vaccination. We therefore aim to investigate the possible relationship of severe autoimmune adverse events post zoster vaccination with a matched case-control study of reported events in the Vaccine Adverse Event Reporting System (VAERS).
Source: Journal of Drugs in Dermatology - July 1, 2015 - Self-Organized Criticality Theory of Autoimmunity
Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host's immune ‘system’ by repeated immunization with antigen, to the levels that surpass system's self-organized criticality.
Source: PLoS One, 2009, 4(12)
